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SARM also called SARMs, stands for Selective Androgen Receptor Modulators, which have similar effects to anabolic steroids, but without their side effects. They are a potential drug to treat muscle wasting and other muscle disorders.
SARMs are considered a miracle weapon for fast muscle building, increase strength and fat loss. The advantages of SARMs over steroids are, SARMs can be taken orally without complications, they do not need to be elaborately injected like classic steroids.
Benefits of SARMs:
- Extremely strong anabolic effect
- Stronger than testosterone
- Building dry muscle mass
- Prevent muscle loss during a definition and diet phase
- Hardly any side effects
- Almost all androgen-related side effects are turned off
- There is no conversion to estrogen
Studies have also shown that SARM have up to 10 times higher binding properties to androgen receptors than testosterone, making them, at least theoretically, more suitable for muscle growth than conventional anabolic and androgenic steroids.
Everything about SARMs and their effects
There is a new trend in the market for bodybuilder supplements: Instead of prohormone or steroid cycles, many athletes are convinced by the positive anabolic effects of SARMs – selective androgen receptor modulators. But what exactly are SARMs, how does the product work and what should be considered? We’ll give you an overview of SARMs.
What are SARMs?
The abbreviation SARMs stands for Selective Androgen Receptor Modulators and these are non-steroidal compounds that selectively dock at the androgen receptors in the body and there develop similar effects as prohormone or steroid cures. In contrast to these cures, however, negative side effects are supposed to happen less when taking SARMs. So are SARMs the new prohormone replacement?
Effects of SARMs
SARMs have been researched and developed by major pharmaceutical companies to bring effective drugs to the market, for example against muscle wastage in old age or after surgery. It was intended to create a form of therapy that favors muscle growth – without the negative androgenic side effects.
Accordingly, SARMs must have advantageous tissue selectivity from a medical point of view. The selectivity of the androgen receptor modulators has been the biggest success: for example, SARMs lead to agonistic activities in bones and musculature, while the impact on secondary sexual tissue is minimal.
SARMS are supposed to have beneficial effects like:
- anabolic effect
- increased growth of lean, fat-free muscle mass
- more endurance and strength
- improved regeneration after injury
At the same time, however, the side effects of pro-hormone and steroid cures are gone:
- no damage to liver and prostate
- no androgenic effects (hair loss, gynecomastia, hypertension, etc)
SARMs for weightlifters and bodybuilders
Bodybuilders and strength athletes take SARMs mainly because of these goals:
- increased muscle growth
- increased fat loss
- improved regeneration of the muscles
- less loss of muscle mass between two steroid or prohormone cures
These are the well-known SARMs currently taken by athletes:
SARM Ostarine is also known under the name MK-2866 and it was developed by the company Gtx. The product uses its anabolic effects to build lean muscle and improves wound healing capabilities. They are tablets and one should be taken once a day.
LGD / Ligandrol
Another SARM is LGD, also known as Ligandrol or LGD-4033. It is a relatively new product on the market, but has shown particularly good results for gaining lean muscle mass.
Other well-known SARMs are Andarine (S4), Cardarine (GW-501516) and Stenabolic (SR-9009).
SARMs as a steroid alternative?
Bodybuilders and strength athletes who pursue ambitious goals and participate in competitions can sometimes fail to achieve their goals despite hard training and strict diets. Prohormone or steroid cycles have long been considered a possible solution to continue building lean muscle mass.
The supply of steroids, however, not only has advantages, but also brings some disadvantages. For example, steroids can have positive anabolic effects, leading to muscle gains. At the same time, however, they also have androgenic, which means “masculinizing”, effects and can cause, for example, hair loss on the head, increased body hair growth, high blood pressure and growth of the prostate. In women, taking steroid cures can lead to a “masculinization”, while men must fight with side effects such as water retention under the skin or enlargement of the mammary glands. In addition, the exogenous intake of steroids leads to a suppression of the body’s own hormone production, which among other things can negatively influence the maturation of the sperm. Accordingly, the use of steroids can lead to infertility.
However, SARMs selectively and specifically affect the steroid receptors. They themselves are not steroid hormones. This helps to circumvent many of the above mentioned negative side effects of prohormone and steroid cures.
Side effects of SARMs
The pharmaceutical industry’s research on SARMs is still in its infancy and side effects and long-term consequences have hardly been researched so far. In addition, SARMs are investigative research drugs, so they are not designated supplements for athletes. SARMs should be taken with great caution at your own risk.
Characteristics of SARMs
The structures of SARMs are very variable. As such, all compounds that dock to the androgen receptors and activate the tissue may be referred to as SARMs. Important features of SARM are:
- They are NOT steroids
- Their structure has a great variability
- They have the ability to dock with the androgen receptor and modulate or activate it
- They are selective: it varies in which tissue the activation takes place
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